Effective and safe regional node irradiation in early breast cancer
A partir d'une revue systématique des essais randomisés ouverts jusqu'en janvier 2009 (16 essais, 14 324 patientes), cette méta-analyse présente l'évolution, avant et après 1980, des résultats après irradiation des ganglions régionaux pour un cancer du sein de stade précoce
Postoperative radiation therapy has been a mainstay of treatment for early breast cancer for many years. The efficacy of chest wall radiation therapy after mastectomy and whole breast irradiation after breast conserving surgery was established through randomised controlled trials. In some of these trials, regional nodes were irradiated, but it is unclear how much of the effect of the radiation therapy occurred because of regional nodal irradiation.
The Lancet , commentaire, 2022