Social Networks, Social Determinants and Mortality: Western New York Exposures and Breast Cancer (WEB) Study
Menée auprès de 1 012 patientes atteintes d'un cancer invasif du sein et auprès de 2 036 témoins, cette étude analyse l'association entre des facteurs sociaux (amis, taille du foyer, revenus du foyer, statut marital, etc.) et la mortalité spécifique ainsi que la mortalité toutes causes confondues
There are few studies of social support and other social determinants of health after breast cancer (BC) diagnosis and their associations with mortality; results have been inconclusive. Further, it is not known if observed associations are specific to women with BC diagnosis or if associations would be similar among healthy women.Women with incident, pathologically confirmed invasive BC, stage I-IV (n = 1012) and healthy frequency age-matched controls (n = 2036), answered a social support questionnaire in prospective follow-up of a population-based case-control study, the Western New York Exposures and Breast Cancer (WEB) Study. At interview, all participants were aged 35-79 years and resident of two counties in Western New York State. Mortality status was ascertained from the National Death Index. Participants were queried regarding the number of their close friends, frequency of seeing them, household size, household income, and marital status. Hazard ratios (HR) and 95% confidence intervals (CI) for BC specific mortality (BC women only) and all-cause mortality were estimated.Lower household income was associated with higher all-cause mortality among women diagnosed with BC (HR 2.48, 95% CI, 1.24-4.97) and similarly among the healthy women (HR 2.63, 95% CI, 1.25-5.53). Number and frequency of seeing friends, marital status, and household size were not associated with mortality, either among BC patients or among healthy women.Among both those diagnosed with BC and healthy women, lower income was associated with more than twice the mortality. Marital status, household size, number or frequency of meeting friends were not associated with survival.