Advanced Adenoma and Long-Term Risk of Colorectal Cancer, Cancer-Related Mortality, and Mortality
Menée auprès de 10 584 personnes ayant réalisé une coloscopie après un test positif de recherche de sang occulte dans les selles, cette étude analyse l'association entre la présence d'adénomes non avancés ou avancés et le risque de cancer colorectal ainsi que la mortalité spécifique et toutes causes confondues
Colonoscopy is effective for reducing the risk of colorectal cancer (CRC) through detection of CRC and removal of adenomatous polyps. Studies have reported the association of advanced adenomas with increased risk of CRC and CRC-related death over the following 5 to 15 years compared with having no advanced adenomas.1,2 The association of nonadvanced adenomas with CRC incidence and mortality after colonoscopy is less clear.1-3 However, to our knowledge, no studies have evaluated the association of adenomas and advanced adenomas with all-cause mortality. We aimed to investigate the association of nonadvanced and advanced adenomas with CRC incidence and mortality and all-cause mortality compared with a negative colonoscopy among participants of the Minnesota Colon Cancer Control Study.
JAMA Network Open 2024