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The Role of Station 10 Lymph Nodes in D2 Dissection

Menée à partir des données d'un essai randomisé portant sur 526 patients atteints d'un cancer gastrique proximal de stade avancé et résécable (74,5 % d'hommes ; âge moyen : 60,6 ans), cette étude analyse la survie sans progression à 5 ans et la survie globale après une gastrectomie laparoscopique totale avec lymphadénectomie hilaire splénique préservant la rate

The quest to optimize safety and extent of lymph node dissection for gastric cancer (GC) has been a long-standing topic of research and discussion. D2 lymphadenectomy has been largely adopted as the standard in the East and West, traditionally involving dissection of nodal stations 1 to 7, 8a, 9, 10, 11p, 11d, and 12a for total gastrectomy. Dissection of nodal station 10 (No. 10) has been controversial due to its rates of postoperative complications, in part attributed to concomitant splenectomy. Although No. 10 dissection is recommended for tumors invading the greater curvature of the stomach, Japanese guidelines currently recommend this procedure for other tumors only when it is safe to do so and when it is performed by an experienced surgeon, as there is no consensus of its efficacy.

https://doi.org/10.1001/jamasurg.2024.1035 2023

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