Are Accurins the cure for Aurora kinase inhibitors?
Menée in vitro et in vivo, cette étude évalue l'activité antitumorale et la toxicité de nanoparticules contenant une thérapie ciblée, ici un inhibiteur de la kinase Aurora B
A nanoparticle formulation of an Aurora B inhibitor increases antitumor efficacy and reduces toxicity, which may be a precedent for the use of this technology with other small molecules (Ashton et al., this issue).