Long-Term Effectiveness of Human Papillomavirus Vaccination: Implications for Future Reduction in Cancer
Menée aux Etats-Unis sur la période 2003-2018 par enquêtes et à l'aide d'échantillons cervicaux et péniens (âge : 14-24 ans), cette étude évalue l'efficacité du vaccin quadrivalent contre le papillomavirus humain depuis la mise en place du programme de vaccination
Infection with human papillomavirus (HPV) is associated with 6 cancer types: cervical squamous cell carcinoma and adenocarcinoma, as well as oropharyngeal, anal, vulvar, vaginal, and penile squamous cell carcinoma. Although rates of cervical cancer decreased after the adoption of population-level screening programs, a recent study found a 2.36% annual increase in all HPV-related cancer types between 2001 and 2017 in the United States, with an incidence of HPV-associated cancer of 13.68 cases per 100 000 among women and 11 cases per 100 000 among men (1). For cervical cancer, we have effective screening programs and treatments of cervical precancer, but significant disparities ...