Unravelling the Mechanisms of Cancer-Related Cognitive Dysfunction in Non–Central Nervous System Cancer
Menée en Allemagne sur la période 2015-2016 auprès de 167 patients atteints d'un cancer du poumon (âge médian : 66 ans ; 63 % d'hommes), cette étude évalue la fréquence des auto-anticorps neuronaux et analyse leur association avec le risque de troubles cognitifs
Over the past 30 years, a growing body of evidence has emerged demonstrating that many patients with systemic cancer experience cancer-related cognitive impairments (CRCIs). Difficulties with memory, language, learning, attention, and processing speed (outside of that which would be expected because of normal aging) are increasingly observed among long-term survivors of cancer. Traditionally, CRCI symptoms were thought to be caused only by the neurotoxic effects of cancer therapies; therefore, they were appropriately termed chemoradiation-related cognitive impairments (also known as “chemobrain” or “brainfog”).