Using Extended Cognitive Behavioral Treatment and Medication to Treat Dependent Smokers
Menée auprès de 406 participants, cette étude américaine évalue l’efficacité d’une psychothérapie combinée à un traitement médicamenteux pour l’aide à l’arrêt du tabac
Objectives. We evaluated smoking-cessation efficacy of an extended course of sustained-release bupropion (bupropion SR) and cognitive-behavioral treatment (CBT). Methods. Participants who smoked at least 10 cigarettes per day and who smoked within 30 minutes of arising (n=406) completed a 12-week smoking cessation treatment including group counseling, nicotine-replacement therapy, and bupropion SR. Participants were then randomly assigned to 1 of 5 conditions: (1) no further treatment, (2) active bupropion SR for 40 weeks, (3) placebo for 40 weeks, (4) active bupropion SR and 11 sessions of CBT for 40 weeks (A-CBT), or (5) placebo and 11 sessions of CBT for 40 weeks. Participants were assessed at baseline and at weeks 12, 24, 52, 64, and 104. Results. A-CBT was not superior to the other 3 extended treatments. From weeks 12 through 104, all extended treatment conditions were superior to standard treatment. At weeks 64 and 104, the 2 CBT conditions produced significantly higher abstinence rates than did the other 3 conditions. Conclusions. Brief contact with providers can increase abstinence during treatment. CBT may increase long-term abstinence after extended treatment is terminated. (Am J Public Health. Published online ahead of print June 7, 2011: e1-e8. doi:10.2105/AJPH.2010.300084)
http://ajph.aphapublications.org/cgi/content/abstract/AJPH.2010.300084v1