Cancer survivorship and bone health
Menée au Royaume-Uni à partir de données 1998-2020 portant sur 578 160 adultes ayant survécu à un cancer et sur 3 226 404 témoins, cette étude de cohorte analyse le risque de fracture osseuse en fonction de la localisation de cancer
Cancer is such a common condition. As health-care professionals, many of our patients have a history of cancer. Rapid advances in cancer treatment, including the advent of immunotherapy, have markedly improved cancer prognosis. However, improved cancer survivorship means these patients might experience chronic issues, such as poor bone health (osteoporosis or osteopenia) and fracture. As cancer tends to affect older individuals, this burden is compounded by age-related bone loss. Aside from fracture-related pain and incapacity, low trauma (equivalent to a fall from a standing height), fragility, and osteoporotic fractures are associated with increased mortality for up to 10 years after fracture.