The Use of Retinoids in Ovarian Cancer: A Review of the Literature
Cet article passe en revue les études récentes concernant l'utilisation des rétinoïdes, une classe de composés chimiques dérivés de la vitamine A, dans le traitement et la prévention des cancers de l'ovaire
ABSTRACT: Ovarian cancer is the deadliest of all gynecologic malignancies. The search for novel treatment modalities to augment traditional chemotherapy and improve quality of life is ongoing. Retinoids, a class of compounds composed of vitamin A, its natural derivatives, and synthetic analogs, have been studied extensively in both the prevention and treatment of gynecologic malignancies. In this article, we reviewed preclinical studies and clinical trials conducted using retinoids in ovarian cancer.