Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway
Cet article passe en revue les travaux récents sur les mécanismes moléculaires de la signalisation PD-1
The PD-1 pathway plays an essential role in maintaining immunologic self-tolerance. However, cancers can subvert the role of this pathway and blind the immune system to their presence. The molecular details of the pathway are discussed.
New England Journal of Medicine , résumé, 2015