Resource requirements to accelerate clinical applications of next generation sequencing and radiomics: Workshop commentary and review
Cet article présente les résultats de la réflexion d'un groupe de travail américain concernant les ressources qui permettraient d'accélérer les applications cliniques de la radiomique et des techniques de séquençage de nouvelle génération
The National Institutes of Health (NIH)/U.S. Food and Drug Administration (FDA) Joint Leadership Council Next-Generation Sequencing (NGS) and Radiomics Working Group (NGS&R WG) was formed by the NIH/FDA Joint Leadership Council to promote the development and validation of innovative NGS tests, radiomic tools, and associated data analysis and interpretation enhanced by artificial intelligence (AI) and machine-learning (ML) technologies. A two-day workshop was held on September 29–30, 2021 to convene members of the scientific community to discuss how to overcome the “ground truth” gap that has frequently been acknowledged as one of the limiting factors impeding high-quality research, development, validation, and regulatory science in these fields. This report provides a summary of the resource gaps identified by the WG and attendees, highlights existing resources and the ways they can potentially be leveraged to accelerate growth in these fields, and presents opportunities to support NGS and radiomic tool development and validation using technologies such as AI and ML.
Journal of the National Cancer Institute , résumé, 2023